Exempt research is Human Subjects Research that meets one of the minimal risk categories in the federal regulations. Research studies determined Exempt from the regulations are considered research with human subjects. An Exemption determination means that not all of the regulations in 45 CFR 46 must be applied to the individual study and the WCM IRB office may instead choose to apply or not apply some standards. Studies reviewed at this level may be required to undergo a limited IRB review. Limited IRB review considers data protection and, where appropriate, broad consent.